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Take the genes of Big Bud, Shiva, and a Hawaiian indica, mix them together, and you've got RD-12, a rare indica-dominant hybrid with an unknown ratio of sativa to indica. This strain is fairly strong, with THC levels of at least 16% in some tests. CBD, meanwhile, is nearly nonexistent, roughly 0.03% in the same tests, so RD-12 shouldn't be used as the sole treatment for epilepsy or other conditions that can be relieved with CBD. The high is almost entirely physical and comes with a pleasant body buzz, calming effects, couch-lock, and sleepiness. That makes this an ideal medical choice for relieving sleeplessness, though it's also helpful with tumors, chronic pain, migraines and other headaches, and inflammation. RD-12 has a sweet taste of earth and wood, while it smells of blueberries and Skunk. Though reports of negative effects are few and far between, that's mostly because this strain is so rare. In any event, dry mouth, dry eyes, and paranoia are typically the most common side effects when smoking marijuana. This strain could conceivably be purchased on the legal markets in California and the rest of the American West, but it's definitely not a common selection.